Cortoss - Technical Specifications - Bioactivity & Bone Bonding

• Combeite bioactive glass-ceramic particles
• Glass-ceramic particles release alkali into the immediate environment, due to ion exchange with body fluid
• Alkali environment induces deposition of Calcium Phosphate
• Calcium Phosphate is slowly converted to bone

• Histologic evidence indicates Cortoss^® achieves fixation in two stages:
  • Immediate mechanical interlock into bone (interdigitation)
  • Direct surface bonding without intervening fibrous layer
• Calcium phosphate-rich layer allows newly formed bone to grow in apposition along the Cortoss^® surface